Biochemistry: How Fats Enter the Powerhouse! Beta oxidation of fatty acids happens in the Mitochondrial Matrix, but there's a catch: Long Chain Fatty Acids (LCFAs) cannot cross the inner mitochondrial membrane on their Function of carnitine in the transport of mitochondrial long chain Download Scientific Diagram Carnitine: Genetic Variants Affecting Mitochondrial Energy and Health Fatty acid oxidation and carnitine palmitoyltransferase I: emerging therapeutic targets in cancer Cell Death & Disease